Atypical Oral Manifestation of Non-Hodgkin Lymphoma
Article Type: Case Report

Mariana Dalbo Contrera Toro1*, Maria Elvira Pizzigatti Correa2, Thiago Luis Infanger Serrano1, Giselle de Martin Truzzi1, Henrique Furlan Pauna1, Jose Vassallo3, Ana Cristina Dal Rio2, Reinaldo Jorge Gusmao4

1Department of Otorhinolaryngology, Head & Neck Surgery, State University of Campinas, UNICAMP, Brazil.

2Department of Otorhinolaryngology and Multidisciplinary Laser Unit, State University of Campinas, UNICAMP, Brazil.

3Department of Pathology, State University of Campinas, UNICAMP, Brazil.

4Department of Otorhinolaryngology, Coordinator of the Multidisciplinary Laser Unit, Post-graduate Program Coordinator, State University of Campinas, UNICAMP, Brazil.

Corresponding Author:

Dr. Mariana Dalbo Contrera Toro

ENT Resident

Department of Otorhinolaryngology, Head & Neck Surgery

State University of Campinas, UNICAMP

PO BOX 6111, Postal Code: 13081-970

Sao Paulo, Brazil.

Received: 2015-10-28 ; Accepted: 2015-11-16 ; Published: 2015-11-27
Citation: MDC, Correa MEP, Serrano TLI, Truzzi GDM, Pauna HF, et al. (2015) Atypical Oral Manifestation of Non-Hodgkin Lymphoma. JOTRL 1:10433.
Copyright: © 2015 Toro MDC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred
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Introduction: Oral ulcerations are a common complaint to either physicians or dentist practices, especially on children, in which the main diagnoses are aphthous stomatitis disease and traumatic injury. Neoplasic lesions may be forgotten due to low prevalence in lower ages and absence of risk factors in this population. The incidence of non-Hodgkin’s lymphoma has increased in particular due to large-cell histologic types, and the most recent increase has been attributed to the acquired immunodeficiency epidemic. In the head and neck area, extra-nodal sites of lymphoma are unusual. Oral locations represent less than 5% of all cases.

Case Presentation: Male, 7-year-old child presented with a single ulcer located at buccal mucosa. Biopsy of the lesion was compatible with anaplasic large cell’s non-Hodgkin lymphoma and the patient was referred to a children’s oncologic center for treatment.

Conclusion: Single oral ulcerations on children requires a careful attention from the general practices with a wide spectrum of differential diagnosis. It is necessary to have a clinical, laboratory and histology view of simple lesions. Non-Hodgkin’s lymphoma is a potential and important etiology due to its malignant characteristics and better prognosis at early stages of the disease.

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